Mary of Guise, born on 22 November 1515, was a prominent figure in Scottish history, serving as Queen of Scotland from 1538 until 1542 as the second wife of King James V. A member of the powerful House of Guise, she was also known as Mary of Lorraine. Her marriage to James V was a strategic alliance that produced three children, although tragedy struck when both sons died in April 1541, and her husband passed away in December 1542.
Following the death of James V, Mary of Guise found herself thrust into the political landscape as the mother of the infant Mary, Queen of Scots. Initially, the regency was entrusted to James Hamilton, 2nd Earl of Arran, but in 1554, Mary took over as regent. Her tenure was marked by her unwavering commitment to her daughter's dynastic interests and the maintenance of the Franco-Scottish alliance.
Mary's regency was characterized by her efforts to navigate the turbulent waters of the Scottish Reformation. While she displayed a degree of tolerance towards the Protestant reform movement, she ultimately struggled to prevent the sweeping changes that were reshaping Scotland's religious landscape. Her reign as regent lasted until her death on 11 June 1560, leaving a lasting impact on the kingdom.