Mithridates II of Parthia, known as Mithridates II the Great, ruled the Parthian Empire from one hundred twenty-four to ninety-one BC. His ascension to the throne followed the sudden death of his predecessor, Artabanus I, during a tumultuous period for the empire. Inheriting a realm beset by military challenges from both the east and west, Mithridates II swiftly took action to stabilize Mesopotamia. He secured the loyalty of Characene and quelled the insurgent Kingdom of Elymais, as well as the Arab tribes that had persistently raided Babylonia.
One of his most significant achievements was the expansion of Parthian influence into the Caucasus, where he successfully established vassal states in Armenia, Iberia, and possibly Caucasian Albania. To the east, Mithridates II confronted and defeated the nomadic tribes in Bactria, who had previously killed both of his predecessors. He also reconquered Sakastan, granting it as a fiefdom to the House of Suren. His military prowess was further demonstrated in one hundred fourteen or one hundred thirteen BC when he seized Dura-Europos in Syria from the Seleucids.
By the time of his reign's conclusion in ninety-five BC, Mithridates II had garnered the allegiance of the northern Mesopotamian kingdoms of Adiabene, Gordyene, and Osrhoene, marking the zenith of the Parthian Empire. Under his leadership, the empire extended from Syria and the Caucasus to Central Asia and India, and he was instrumental in establishing diplomatic relations with both Rome and Han China.
A staunch advocate of Achaemenid traditions, Mithridates II sought to reinforce the connection between the Arsacid dynasty and the ancient Iranian Achaemenid Empire. He was the first Parthian king to adopt the title King of Kings and to depict himself wearing an Iranian tiara on his coins, a departure from the Hellenistic diadem favored by his predecessors. Additionally, he replaced the omphalos on his coinage with a high-backed throne of Achaemenid design, further solidifying his commitment to the legacy of the Achaemenids.