Osroes I, born in the year fifty, was a significant figure in the history of the Parthian Empire, ruling its western territories from one hundred nine to one hundred twenty-nine, with a brief interruption. His reign was marked by a fierce rivalry with Vologases III, who governed the eastern provinces and posed a constant challenge to Osroes' authority.
In the year one hundred sixteen, Osroes I faced a formidable threat when Roman Emperor Trajan invaded and temporarily displaced him from his throne in Ctesiphon. During this tumultuous period, Trajan appointed Osroes' son, Parthamaspates, as a puppet ruler. However, following Trajan's death in the subsequent year, the Parthian nobility rallied to restore Osroes I to power, reaffirming his position as sovereign.
Despite his reinstatement, Osroes I's reign came to an end in one hundred twenty-nine when he was ultimately ousted by Vologases III. This power struggle exemplified the turbulent nature of Parthian politics during the era, as rival factions vied for control over the vast empire.