Plutarch of Byzantium, a notable presbyter, served as the Bishop of Byzantium for a significant period of sixteen years, from eighty-nine to one hundred five AD. He succeeded Polycarpus I of Byzantium, continuing the legacy of leadership within the early Christian community.
During his tenure, Plutarch faced the challenges posed by the persecution of Christians under the Roman Emperor Trajan, which began in ninety-eight AD. This period was marked by trials for many believers, yet Plutarch remained a steadfast figure in guiding his flock through these turbulent times.
Upon his passing, Plutarch was laid to rest in the church of Argyroupoli, a final resting place that he shared with his predecessors, signifying the continuity of faith and leadership in Byzantium.